Skip to content

Anthropic medicinal-chemistry evaluation

Selects compounds with the highest or lowest measured ADME-related property from molecular structures and reference values.

2 models

Higher is better.

  1. 1Claude Sonnet 5.5Anthropic65.3
  2. 2Claude Opus 5.5Anthropic63.5
Higher is better. Bar colour: blue proprietary, orange open weights, green other.

About this benchmark

Metric
Accuracy
Tasks
504 molecular-property questions
Authors
Anthropic (2026)

Scores are as reported by model developers or evaluators and may use different settings (for example reasoning effort or tools). Compare with care.