ProteinGym Hard
Predicts mutation effects by ranking mutant protein sequences against wild type and comparing against laboratory measurements.
1 models
Higher is better.
About this benchmark
- Metric
- Rank correlation
- Tasks
- Hard protein mutation-effect ranking tasks
- Authors
- Anthropic (2026)
Scores are as reported by model developers or evaluators and may use different settings (for example reasoning effort or tools). Compare with care.